Is your heartburn a sign of a more serious condition?

You may have abnormal esophageal cells.

EsoGuard is a highly accurate test that detects altered DNA to help diagnose precursors to cancer.


Gastroesophageal reflux disease (GERD)

happens when digestive liquid from the stomach moves into the esophagus, causing irritation of the lining of the esophagus.


Symptoms of GERD

  • Heartburn

  • Regurgitation

  • Chest Pain

  • Nausea after eating

  • Sour tase in mouth

  • Coughing, choking or wheezing

  • Difficulty swallowing

  • Hiccups

  • Belching or burping excessively

  • Hoarseness or change in voice

  • Sore throat

  • Feeling that food is stuck behind the breastbone

  • Loss of enamel and tooth decay

Barrett’s Esophagus (BE) 

is a precancerous condition caused by damage to the lining of the esophagus from digestive liquids. People with GERD are more likely to have BE and it occurs more often in men than women and in people over age 50. 


BE itself doesn’t cause symptoms, so many people are unaware that they have the disease and therefore unaware of their risk of developing cancer.


It is estimated that more than 18,000 people in the United States will be diagnosed with esophageal cancer and more than 16,000 people will die from the disease in 2020.


Early detection and diagnosis of BE and pre-cancerous cells is critical, allowing for surveillance and treatment before lethal esophageal cancer can develop. 


EsoGuard patient.png

Testing for Barrett's Esophagus


EsoGuard is a DNA test that detects abnormal esophageal cells, such as Barrett's Esophagus, precancerous cells with dysplasia and cancer.

eso cells.png

Did you know that chronic heartburn can be a symptom of a more serious condition called Barrett’s Esophagus?

People with Barrett's Esophagus (BE) are at increased risk of developing esophageal adenocarcinoma (EAC) a deadly form of cancer.

How it works

No blood or needles. 

Your doctor will perform a procedure to collect cells from your lower esophagus and ship them to our lab. 


Cell Collection

Your doctor will perform a cell collection procedure to gather cells from your lower esophagus for analysis. 




The collected cells are shipped to our laboratory where the DNA is tested using the EsoGuard advanced molecular diagnostic test.

EsoGuard Test.png



Your healthcare provider will contact you with the results of your test, normally within 3 weeks.


If irregular cells are discovered your doctor will discuss appropriate treatment pathways. Finding BE early is key to reducing the risk of developing esophageal cancer. 

EsoGuard Results.png

Your DNA for early detection. 

Esophageal cancer is the 7th most common cause of cancer death among men in the United States. When it comes to cancer we know that early detection is key.
Ask your doctor if the EsoGuard test is right for you.
insurance icon_600x600.png

Most insured patients pay $0

Lucid Diagnostics directly bills your medical insurance carrier for its analysis. Due to its proprietary nature, the laboratory is currently in process of becoming an “in network” provider with most medical insurance plans. In the interim, you will not be responsible for any “out of network” laboratory fees associated with these plans.  

Featured on

Get Tested

Find a doctor who offers the EsoGuard DNA test near you.

Fill out the form and we'll be in touch soon.

We'll be in touch soon!

Take action for your health

Ask your doctor if the @EsoGuard_test is right for you


1. Science Translational Medicine 17 Jan 2018: Vol. 10, Issue 424, eaao5848, DOI: 10.1126/scitranslmed.aao5848 


3. Manoop S. Bhutani, MD, FACG, FACP, and Radha Tamerisa, MD, University of Texas Medical Branch, Galveston, TX – Published June 2004. Updated May 2008.